Use of Concentrated Growth Factor (Cgf) in Reconstruction on Two-Wall Bone Defect After Cystectomy, An Alternative to Traditional Regeneration- Case Report

Authors

  • Coniglione F. PhD, Catholic University “Our Lady of Good Counsel” Tirana; Department of Surgical Science Author
  • Luciani F. University of Roma “Tor Vergata” U.O. Oral-Maxillofacial Surgery, Post Graduate Course in “Oral Surgery”. Director and Chief: Prof. Claudio Arcuri Author
  • Ferrari G. University of Roma “Tor Vergata” – U.O. Oral-Maxillofacial Surgery, Post Graduate Course in “Oral Surgery”. Director and Chief: Prof. Claudio Arcuri Author
  • Leggeri A. Freeland Dentist in Tivoli (Rome - Italy) Author
  • Condò R. University of Roma “Tor Vergata” – U.O. Oral-Maxillofacial Surgery, Post Graduate Course in “Oral Surgery”. Director and Chief: Prof. Claudio Arcuri Author
  • Papa E. University of Roma “Tor Vergata” U.O. Oral-Maxillofacial Surgery, Post Graduate Course in “Oral Surgery”. Director and Chief: Prof. Claudio Arcuri Author
  • Agrestini C. University of Roma “Tor Vergata” U.O. Oral-Maxillofacial Surgery, Post Graduate Course in “Oral Surgery”. Director and Chief: Prof. Claudio Arcuri Author

Keywords:

jaw cysts; platelet-derived growth factor; cgf

Abstract

Aim: The purpose of this clinical case report was to describe an alternative technique performed to ensure bone regeneration after removing a cystic lesion in the upper jaw. Bone defect after cystectomy was filled with autologous fibrin rich clots containing CGF. Materials and methods: A 45 years old female patient was suspected to have a cystic lesion with massive bone destruction on the vestibular and palatal walls between teeth 2.2 and 2.3. Concentrated growth factor (CGF) was used to cover the defect in order to favourite the bone grow. Results: After 12 months, the clinical and radiological follow-up examination showed that the tooth was asymptomatic and that the healing was in progress. Conclusions: this article describes a different way to treat a two-wall defect involving both the palatal and buccal bone, after removing a cystic lesion, with the use of CGF as an alternative to traditional use of autologous or heterologous bone. CGF fibrin could promote new bone formation in jaw defects, with benefit to the healing of bone tissue and, thus, is a promising bone repair material.

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Published

2023-04-01